The medaka Oryzias latipes is a freshwater teleost fish native to Southeast Asia (Japan, China, Korea, Vietnam). Its ability to survive in a variety of environmental conditions and the fast responses to different drugs, both at the organ level and at the cellular and molecular levels, justify its wide use in toxicology and ecotoxicology. The ease of obtaining and manipulating the medaka (adults and embryos of all stages), the possibility of directing cross-breeding, and its the short life cycle make it a highly appreciated model by geneticists and embryologists, particularly those interested in the development of vertebrates.
Genomic databases :
In situ hybridization database :
Tokyo Bio-Resource Library (including a library of transgenic medaka lines) :
[FR] Anne-Laure Bauchet thesis (available here : http://theses.vet-alfort.fr/telecharger.php?id=1010)
« The medaka draft genome and insights into vertebrate genome evolution », Kasahara et al., Nature, 2007
« Medaka – a model organism from the far East », Wittbrodt, Shima et Schartl, Nature Rev. Genet., 2002