2021 EFOR meeting in videoconference

10th Annual Meeting of the EFOR network

The tenth edition of the EFOR meeting is now over !

We hope you enjoyed the meeting, and would like to address our deepest thanks to all of you ! A big thank you also for all your feedback, which will help us to improve for the next editions.

Certificates of attendance:

We contacted all attendees about the delivery of the certificates. If you have not received any news from us, please contact us before 1 September 2021 to collect your certificate.

Replays:

The meeting has been fully recorded and will be available as replays, available only to people who registered for the 10th EFOR Meeting.

As a reminder, viewing these replays does not make you eligible to obtain a certificate of attendance.

The replays will be made available on the Imagina platform from 18 June 2021.

We would like to thank all our partners for supporting this event.

Our special thanks go to CELPHEDIA infrastructure, for all the help CELPHEDIA has provided over the past few years to organize the EFOR annual meeting.

Full schedule

Provisional schedule (ongoing)

Monday, May 10 : Technologic and scientific sessions

Morning: Technologic session "New technologies for genome editing"

Organized by: Carine GIOVANNANGELI (TACGENE, Muséum National d’Histoire Naturelle, Paris, France) and Jean-Paul CONCORDET (TACGENE, Muséum National d’Histoire Naturelle, Paris, France)

Speakers:

10.00 am – 10.30 am : Filippo DEL BENE (Institut de la Vision, Paris, France) – Recent advances in genome editing for precise mutagenesis in zebrafish ;
10.30 am – 11.00 am : Abderrahman KHILA (Institut de Génomique Fonctionnelle de Lyon, Lyon, France) – Developmental genetic basis of extreme growth variation in water striders ;
11.00 am – 11.30 am : Jian-Kang ZHU (Shanghai Center for Plant Stress Biology, China) – Precision genome editing in plants
11.30 am – 11:50 am : Yacine BADIS (Station Biologique de Roscoff, Roscoff, France) – Targeted CRISPR-CAS9-based gene knockouts in the model brown alga Ectocarpus

Afternoon: Scientific session "Global change"

Organized by : Sam DUPONT (University of Gothenburg, Sweden)

Speakers:

2.00 pm – 2.30 pm : Fredrik JUTFELT (Norwegian University of Science and Technology, Norvège) – Thermal biology of wild and laboratory zebrafish ;
2.30 pm – 3.00 pm : Robert ELLIS (University of Exeter, Exeter, UK) – Lessons from two high CO2 worlds: future oceans and intensive aquaculture ;

3.00 pm – 3.15 pm : Break (15 minutes)

3.15 pm – 3.45 pm : Piero CALOSI (Université du Quebec, Rimouski, Canada) – The dirty work needed to (try to) develop a marine model for marine global change biology… and some questions answered ! ;
3.45 pm – 4.15 pm : Nicolas SCHTICKZELLE (Université de Louvain, Belgium) – Experimental ecology with protist microcosms as a tool for global change biology

Simultaneously with the two other sessions, all day: Session "Reduce, Refine, Replace"

Organized by: This session will partially resume the schedule of the 2020 3R meeting which has been cancelled due to the pandemic.

The 3R session is organized by:

Ivan BALANSARD (INSB, GIRCOR, France)
Thomas BROCHIER (Mediterranean Primate Research Center, France)
Yann HERAULT (Institut Clinique de la Souris/PHENOMIN, France)
Jean-Stéphane JOLY (EFOR/TEFOR Paris-Saclay, France)
Bertrand PAIN (SBRI, France)
Brigitte RAULT (Inserm Ethics Committee (CEI), France)

Speakers:

Mouse models

9.35 am – 10.05 am : Jean-Marie HÉLIÈS (GIRCOR, France) – French transparency Charter : how to communicate on the use of animals for scientific purposes ?
10.05 am – 10.30 am : Myriam MATTEI (Institut Pasteur, France) – 3Rs in practice : Institut Pasteur

10.30 am – 10.45 am : Break (15 minutes)

10.45 am – 11.10 am : Sabine RICHARD (AniRA PBES, Lyon, France) – Examples of implementation of the 3Rs in rodent research facilities in Lyon
11.10 am – 11.35 am : Michael RAESS (INFRAFRONTIER, Germany) – INFRAFRONTIER and the 3Rs
11.35 am – 11.50 am : Philippe SCHMITT (CELPHEDIA, France) – R&D project for 3R in CELPHEDIA, the national infrastructure for animal research
11.50 am – 12.05 am : Thierry GALLI (ITMO BCDE, IPNP/INSERM U1266, France) – Towards a French Center for the 3R: FC3R

Non human primate models

2.00 pm – 2.30 pm : Manon DIRHEIMER (Inserm, France) – Continuous work in 3R implementation, example of 3 public research laboratories
2.30 pm – 3.00 pm : Helen BEYER (SILABE-Université de Strasbourg, France) – Implementing the 3Rs running a service platform

3.00 pm – 3.10 pm : Break (10 minutes)

3.10 pm – 3.40 pm : Rachel TANNER (University of Oxford, UK) – A 3Rs approach to tuberculosis vaccine testing in non-human primates
3.40 pm – 4.10 pm : Amélie REYNAUD (CRNL-ImpAct team, France) – Refinement of monkey training in neurosciences

4.10 pm – 4.20 pm : Break (10 minutes)

Zebrafish models and organoids

4.20 pm – 4.50 pm : Catherina BECKER (University of Edimburgh, UK) – Larval Zebrafish for Discovery Research
4.50 pm – 5.20 pm : Lynne SNEDDON (University of Gothenburg, Sweden) – Assessing and alleviating pain in laboratory zebrafish

5.20 pm – 5.30 pm : Break (10 minutes)

5.30 pm – 6.00 pm : Catarina BRITO (NOVA University of Lisbon, Portugal) – 3D-3-culture models
6.00 pm – 6.30 pm : Giuliana ROSSI (Roche – Institute for Translational Bioengineering, Basel, Germany) – Capturing cardiogenesis in gastruloids

Tuesday, May 11: sessions focusing on a particular groupe of model organism

Session: "Mouse models"

Organized by: Yann HÉRAULT (Institut Clinique de la Souris/PHENOMIN, France) and Jacqueline MARVEL (SFR Biosciences, France)

Invités :

9:30 am – 11:00 am – Mouse genetics & infection

9.30 am – 10.00 am : Xavier MONTAGUTELLI (Mouse Genetics Laboratory, Institut Pasteur, Paris, France) – Mouse models for Covid-19 ;
10.00 am – 10.30 am : Ana ZARUBICA (CIPHE – PHENOMIN (Inserm, CNRS, AMU), Marseille, France) – Humanized mouse model of COVID-19 infection ;
10.30 am – 11.00 am : Branka HORVAT (CIRI, Lyon, France) – Intranasal fusion inhibitory peptides block SARS-CoV-2 infection in hACE2 transgenic mice ;

11.00 am – 11.15 am : Break (15 minutes)

11:15 am – 12:15 am : Social interaction

11.15 am – 11.45 am : Elodie EY (IGBMC, Illkirch-Graffenstaden, France) & Fabrice DE CHAUMONT (Institut Pasteur, Paris, France) – New insights into mouse social communication – a case study in mouse models of autism ;
11.45 am – 12.15 am : Nicolas TORQUET (Institut Clinique de la Souris, Illkirch-Graffenstaden, France) – Souris City, an example of a complex environment for the study of animal behavior

Session: "Zebrafish models"

Organisateurs : Pierre BOUDINOT (INRAE/UVSQ UMR Virologie et Immunologie Moléculaires, Jouy-en-Josas, France), Pedro HERNANDEZ-CERDA (Institut Curie, Paris, France) and Jean-Pierre LEVRAUD (Institut Pasteur, Paris, France)

Speakers:

10.00 am – 10.30 am : Soraya RABAHI (Institut Curie, Paris, France) – Study of interleukin-22 role in gut physiology: Functional analysis in zebrafish
10.30 am – 11.00 am : Ema ETCHEGARAY (IGFL, ENS de Lyon, France) – Use of the Zebrafish model to study a new transposon-derived gene family involved in the development ofthe vertebrate nervous system
11.00 am – 11.30 am : David PEREZ-PASCUAL (Genetic of Biofilm Unit, Microbiology Department at Institut Pasteur, Paris, France) – Gnotobiotic zebrafish model reveals microbiota driven resistance to infection
11.30 am – 12.00 am : Marion ROSELLO (Institut de la Vision, Paris, France) – Second-generation gene editing tools for precise mutagenesis in zebrafish

12.00 am – 2.00 pm : LUNCH BREAK

2.00 pm – 2.30 pm : Adna DUMITRESCU (Centre for Clinical Brain Sciences, Edinburgh, UK) – Shining light on zebrafish: new transgenic optogenetic methods for neural activity control
2.30 pm – 3.00 pm : Jorge TORRES PAZ (DECA – NeuroPSI, Gif-sur-Yvette, France) – A role for early development in phenotypic evolution of cavefish
3.00 pm – 3.30 pm : Mariana Roza de Abreu (LPGP, Rennes, France) – Hippo pathway-mediated regulation of micropyle formation by microRNA 202 (miR-202) in the fish oocyte

3.30 pm – 4.00 pm : Break (30 minutes)

4.00 pm – 4.30 pm : Jaanus SUURVALI (Population Ecology and Evolutionary Genetics group, Department of Biological Sciences, University of Manitoba, Winnipeg, Manitoba, Canada) – The genetic consequences of laboratory domestication in zebrafish
4.30 pm – 5.00 pm : Aurora KRAUS (Irene Salinas’ Lab, Albuquerque, New Mexico, USA) – SARS-CoV-2 Spike protein is sufficient to cause olfactory damage, inflammation and anosmia in zebrafish

Session: "Marine metazoa models"

Organized by:

Eric RÖTTINGER (IRCAN, Université Côte d’Azur – CNRS – INSERM, Nice, France) et Letizia ZULLO (NSYN, Fondazione Istituto Italiano di Tecnologia, Genova, Italy)

Speakers:

10.00 am – 10.30 am : Suzanne MILLS (CRIOBE, Université de Perpignan – EPHE, Perpignan, France) – Anemonefish responses to anthropogenic environmental changes
10.30 am – 11.00 am : Eric GILSON (IRCAN, Université Côte d’Azur – CNRS – INSERM, Nice, France) – Reef coral as a model for aging research
11.00 am – 11.30 am : Eric RÖTTINGER (IRCAN, Université Côte d’Azur – CNRS – INSERM, Nice, France) – Whole body regeneration in Nematostella vectensis
11.30 am – 12.00 am : Irene KOPELMAN (IRCAN (Université Côte d’Azur, CNRS, INSERM) – LBDV (Sorbonne Université, CNRS), France) – Looking at regeneration with a different eye

12.00 am – 2.00 pm : LUNCH BREAK

2.00 pm – 2.30 pm : Letizia ZULLO (NSYN, Fondazione Istituto Italiano di Tecnologia, Genova, Italy) – Stress, autotomy and regeneration in Octopus vulgaris
2.30 pm – 3.00 pm : Cécile BELLANGER (IBFA, Université de Caen Normandie, France) – Cephalopods and environmental stress: effects of pharmaceutical residues on cuttlefish behaviours
3.00 pm – 3.30 pm : Miki KUBA (Okinawa Institute of Science and Technology, Japan) – Smart like a fish, how do stress, age and social behaviour effect non-model fish

Session: "Coleoptera models"

Organized by: Nicolas MONTAGNÉ (Institut d’Ecologie et des Sciences de l’Environnement (iEES-Paris), Paris, France)

Speakers:

Martin N. ANDERSSON (Lund University – Functional Zoology Unit, Sweden) – Ips typographus: an emerging beetle model for peripheral chemosensory research ;
Emmanuelle JACQUIN-JOLY (INRAE – iEES Paris, France) – Reverse chemical ecology at the service of the UNESCO Intangible Cultural Heritage of Humanity: the case of the red palm weevil ;
Arnaud ESTOUP (UMR CBGP – INRAE Montpellier, France) – The genetics of invasive species: the arlequin ladybird Harmonia axyridisas as a model species ;
Abdelaziz HEDDI (INSA Lyon, Laboratoire Biologie Fonctionnelle Insectes et Interactions, France) – Immune functions involved in the endosymbiosis of the cereal weevil Sitophilus spp. ;
Yannick MORET (UMR Biogeosciences – Université de Bourgogne, Dijon, France) – The yellow mealworm beetle, Tenebrio molitor: a model to study immune priming ;
Michaël MANUEL (Institut de Systématique Evolution Biodiversité, Sorbonne Université, France) – Evolution of chemoreception and water-to-land transition in insects: focus on diving beetles (Dytiscidae)

Session: "Plant models"

Organized by: Anne-Cécile MEUNIER (CIRAD, Montpellier, France) and Eric GUIDERDONI (CIRAD, Montpellier, France)

Speakers:

10.00 am – 10.30 am : Anouchka GUYON (UMR IJPB – INRAE Versailles, France) – A blue-print for gene function analysis through Base Editing in the model plant Physcomitrium (Physcomitrella) patens ;
10.30 am – 11.00 am : Jean Luc GALLOIS (GAFL – INRAE Avignon, France) – Resistance to viruses by loss-of-susceptibility in tomato: from natural variation to edited genes ;
11.00 am – 11.30 am : Léo HERBERT (UMR AGAP – CIRAD Montpellier, France) – Enhance Nitrogen Use Efficiency by precise editing of the rice transceptor NRT1.1b at near base ;
11.30 am – 12.00 am : Matthieu CHABANNES (UMR BGPI – CIRAD Montpellier, France) – Edition of endogenous banana streak virus sequences (eBSV) in banana to lift the constraint linked to the presence of these sequences ;
12.00 am – 12.30 am : Mathieu ROUSSEAU-GUEUTIN & Maud FACON (UMR IGEPP – INRAE, Université de Rennes, France) – Tuning a ménage à 4: how to deal with DUPLicated gene Expression ;

12.30 am – 2.00 pm : Lunch break

2.00 pm – 2.30 pm : Gilles PILATE (UMR BioForA – INRAE – ONF Orléans, France) – Toward transgene-free genome editing in poplar plants using Agrobacterium-mediated delivery of a CRISPR/Cas9 cytidine base editor ;
2.30 pm – 3.00 pm : Amélia GASTON (UMR Biologie du Fruit et Pathologie – INRAE, Villenave d’Ornon, France) – Balance between sexual and asexual reproduction in strawberry: the added value of genome editing
3.00 pm – 3.30 pm : Florian VEILLET (UMR IGEPP – INRAE, Université de Rennes, France) – Genome editing to confer disease resistance and tuber quality improvement in the cultivated potato ;
3.30 pm – 4.00 pm : Jean-Philippe MAUXION (UMR BFP – INARE Bordeaux, France) – CRISPR/Cas9-genome editing in tomato ;

4.00 pm – 4.30 pm : Break (30 minutes)

4.30 pm – 5.00 pm : Norbert BOLLIER (VIB-UGent Center for Plant System Biology, Gent, Belgium) – Efficient simultaneous mutagenesis of multiple genes in specific plant tissues by multiplex CRISPR ;
5.00 pm – 5.30 pm : Jean-Paul CONCORDET (TACGENE, MNHN Paris, France) – Stimulating HDR for precise gene editing.

Session: "Algae models"

Organized by: Catherine BOYEN (Station Biologique de Roscoff, Roscoff, France) and Angela FALCIATORE (Université Pierre et Marie Curie, Paris, France)

Speakers:

Keynote speaker:

10.00 am – 11.00 am : Susana COELHO (LBI2M – CNRS/Sorbonne Université – Max Planck Institute for Developmental Biology, Germany) – Sexy brunettes: brown algae as models systems to study the origin and evolution of the sexes.

Algae, microbiome, interactions:

11.00 am – 11.20 am : Sheree YAU (Observatoire Océanologique de Banyuls-sur-Mer, Banyuls-sur-Mer, France) – Ostreococcus and its viruses: an emerging algae–virus system to study genetics, function and interactions
11.20 am – 11.40 am : Claire GACHON (Scottish Association for Marine Science, Scottish Marine Institute, Oban, UK) – Diseases of red and brown macroalgae: diagnosis, physiology and management
11.40 am – 12.00 am : Simon DITTAMI (Station Biologique de Roscoff, Roscoff, France) – Algal-bacterial interactions in brown algal model systems.

12.00 am – 2.00 pm : Lunch break

Evolution:

2.00 pm – 2.20 pm : Richard DORRELL (Institut de Biologie de l’Ecole Nationale Supérieure, Paris, France) – Within-oceanic horizontal gene transfer as a driver of convergent evolution in distantly related Arctic microalgae ;
2.20 pm – 2.40 pm : Oliver CASPARI (Institut de Biologie Physico-Chimique, Paris, France) – Using Chlamydomonas to investigate the evolution of mitochondrial and chloroplast targeting peptides
2.40 pm – 3.00 pm : Pierre-Marc DELAUX (Laboratoire de Recherches en Sciences Végétales, Castanet-Tolosan, France) – Comparative phylogenomics of the water-to-land transitions.

Genomes – genomes regulation:

3.00 pm – 3.20 pm : Leila TIRICHINE (US2B – Université de Nantes, Nantes, France) – Diversity and role of polycomb proteins in unicellular species: insights from the model diatom Phaeodactylum tricornutum
3.20 pm – 3.40 pm : Zhou XU (CNRS – Sorbonne Université, Paris, France) – Telomeres and subtelomeres in the microalga Chlamydomonas reinhardtii ;
3.40 pm – 4.00 pm : Fred VERRET (IMBBC – Hellenic Centre for Marine Research, Heraklion, Grèce) – Endogenous RNA interference in the diatom model species Phaeodactylum tricornutum ;

4.00 pm – 4.30 pm : Break (30 minutes)

New tools, new models:

4.30 pm – 4.50 pm : Yacine BADIS (Station Biologique de Roscoff, Roscoff, France) – Targeted CRISPR-CAS9-based gene knockouts in the model brown alga Ectocarpus ;
4.50 pm – 5.10 pm : Nathanaël ZWEIG (IBENS, Paris, France) – DiatOmicBase, an online tool gathering diatoms omics data
5.10 pm – 5.30 pm : François-Yves BOUGET (Observatoire Océanographique de Banyuls-sur-Mers, Banyuls-sur-Mer, France) – Mamiellophyceae model organisms to study photoperiodism in the Ocean

Session: "Amphibian models"

Organisé par : Nicolas POLLET (EGCE – CNRS, Gif-sur-Yvette, France)

Speakers:

2.00 pm – 2.15 pm : Marie-Elise SCHWARTZ (TEFOR Paris-Saclay, CNRS, INRAE, Université Paris-Saclay, France) – Xenopus news from TPS-AQUA ;

2.15 pm – 2.30 pm : Luc PAILLARD (Institut Génétique et Développement de Rennes, CNRS et Université Rennes 1, France) – Modeling ocular lens disease in Xenopus ;

2.30 pm – 3.00 pm : Matt GUILLE (Institute of Biomedical & Biomolecular Sciences, University of Portsmouth, UK) – Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly ;

3.00 pm – 3.15 pm : Alexandre CHUYEN (IBDM, Aix-Marseille Univ, CNRS) – The Scf/Kit pathway implements self-organized epithelial patterning ;

3.15 pm – 3.45 pm : Anneke SCHOEMAN (North-West University, South Africa) – Repeated reduction in parasite diversity in invasive populations of Xenopus laevis: a global experiment in enemy release ;

3.45 pm – 4.15 pm : AFTERNOON BREAK

4.15 pm – 4.45 pm : Jacques ROBERT (University of Rochester, Medical Center, USA) – TLR5 mediated Reactivation of Quiescent Ranavirus FV3 in Xenopus peritoneal macrophages ;

4.45 pm – 5.00 pm : Matthieu PAIOLA (University of Rochester, Medical Center, USA) – MHC class I-like XNC4 function in immune tolerance and resistance in Xenopus tuberculosis-like disease

Frequently asked questions

I cannot register and/or cannot access the registration platform, what can I do ?

Please send us an email through vjourdain@tefor.net

Where will be hosted the videoconference ?

The EFOR Meeting 2021 will be hosted on the Imagina platform.

I registered for the meeting but couldn’t attend. Is there a way to access the retransmissions of the meeting ?

All the speeches will be available in replay on the Imagina platform during several weeks following the meeting.

To which sessions may I attend once registered ?

Once registered, you can access all the sessions during the two days. Please note that most of the sessions run in the same time and that you will not be able to attend all the talks.

Is attending this meeting eligible for validation of hours of training in animal experimentation?

A certificate of regulatory training in animal experimentation (limited to a maximum of eight hours) will be provided to participants attending the 3R session on 10 May.

Warning: We cannot give you certificates if you only consult the broadcasts following the event!

Can I use or broadcast the retransmissions of the seminar on my own account?

You will not be allowed to broadcast all or part of the videos of retransmissions, unless you have the explicit agreement of the EFOR network, the organisers and the speakers of the corresponding session.

Which personal data is the EFOR network allowed to use?

Before/during the meeting:

As explicitly stated in the registration form, the EFOR network may use your email address to give you news about the event.
Your name, surname and position information may be used in order to assess your participation in the meeting and to provide you with certificates of attendance.

After the meeting:

By selecting the option “I allow the EFOR network to use my email address to keep me informed about EFOR news” when you register, you give the EFOR network the right to use your email address to keep you informed about its activities (mainly to keep you informed about upcoming events: you can ask to be excluded from our mailing list at any time, upon request).
By selecting the option “I allow the EFOR network to transmit my email address to the partners of the EFOR meeting” when you register, you give the EFOR network the right to share these data to the sponsors of the meeting.

Our sponsors

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